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. 2018 Apr 26;62(5):e00156-18. doi: 10.1128/AAC.00156-18

TABLE 6.

Papp of D13 and BHBM in monkey BBB kit

Drug Time (min) Papp (10−6 cm/s)
Cyclosporine 5 1
Cyclosporine 15 1
Cyclosporine 30 1
Caffeine 5 20
Caffeine 15 25
Caffeine 30 25
BHBM 5 22
BHBM 15 9
BHBM 30 9
D13 5 6.8
D13 15 2.2
D13 30 1.1