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. 2018 Apr 26;62(5):e01941-17. doi: 10.1128/AAC.01941-17

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Copyright © 2018 Colley et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 7 — Antifungal activity of PC1244 against A. fumigatus with extended prophylactic treatment in vivo. The effect of 7 days of extended prophylaxis with intranasal PC1244 on the lung fungal load (number of CFU per gram of tissue) (A), the GM level (COI) in serum (B), and the malondialdehyde (MDA) concentration in BALF (C) of A. fumigatus-infected immunocompromised mice (n = 4 or 5) was compared with that of only 1 day of prophylactic treatment. Each horizontal bar presents the mean ± SD for 4 to 6 mice per group. *, P < 0.05.