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. 2018 Apr 26;62(5):e01941-17. doi: 10.1128/AAC.01941-17

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Copyright © 2018 Colley et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 8 — Effect of single prophylactic treatment with PC1244 and posaconazole against A. fumigatus in vivo. PC1244 at 0.4 mg/ml (14 μg/mouse) and posaconazole at 0.8 mg/ml (28 μg/mouse) were intranasally administered 16 h before A. fumigatus inoculation, and the lungs were collected for galactomannan (GM) level (COI) (A) and fungal load (number of CFU per gram of lung tissue) (B) assessment at 8 h after A. fumigatus inoculation. Each bar presents the mean ± SD for 3 to 4 mice per group. *, P < 0.05.