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. 2018 Apr 26;62(5):e02423-17. doi: 10.1128/AAC.02423-17

TABLE 2.

In vitro susceptibilities of 120 clinical isolates of T. interdigitale and T. rubrum

Strain or antifungal drug MIC range (μg/ml) MIC50/MIC90 (μg/ml) Geometric mean (μg/ml) MICs (μg/ml)a
64 32 16 8 4 0.5 0.25 0.125 0.06 0.03 0.015 0.008 0.004 0.002 0.001 0.0005 0.0002 0.0001
All strains (n = 120)
    Efinaconazole 0.002–0.06 0.008/0.016 0.007 4 2 11 61 36 6
    Lanoconazole 0.001–0.008 0.002/0.004 0.002 6 21 82 11
    Luliconazole 0.0005–0.004 0.0005/0.001 0.0005 2 4 22 80 10 2
    Fluconazole 8–64 16/32 12.77 5 8 52 53 2
    Itraconazole 0.03–0.5 0.125/0.25 0.095 3 10 56 43 8
    Terbinafine 0.004–0.125 0.015/0.0165 0.011 1 3 8 50 53 5
T. interdigitale (n = 66)
    Efinaconazole 0.002–0.006 0.008/0.016 0.008 3 1 9 41 10 2
    Lanoconazole 0.001–0.008 0.002/0.004 0.002 4 10 48 4
    Luliconazole 0.0002–0.004 0.0005/0.001 0.0006 2 2 16 41 5
    Fluconazole 4–64 8/16 11.07 2 3 21 38 2
    Itraconazole 0.03–0.5 0.12/0.25 0.111 3 7 38 15 3
    Terbinafine 0.004–0.12 0.015/0.03 0.013 1 2 6 35 20 2
T. rubrum (n = 54)
    Efinaconazole 0.002–0.06 0.004/0.008 0.005 1 1 2 20 26 4
    Lanoconazole 0.002–0.008 0.002/0.004 0.002 2 11 34 7
    Luliconazole 0.0005–0.002 0.0005/0.001 0.0004 2 6 39 5 2
    Fluconazole 8–64 16/32 15.19 3 5 31 15
    Itraconazole 0.03–0.25 0.06/0.125 0.077 3 18 28 5
    Terbinafine 0.004–0.06 0.008/0.016 0.009 1 2 15 33 3
a

Numbers in boldface are modal values.