TABLE 1.
MIC and MEC results of antifungal testing
| Source of isolates and variable | MIC (μg/ml)a for: |
MEC (μg/ml)b for: |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| LULI | LANO | EFINA | VRC | ITC | AMB | NATA | CFG | MFG | AFG | |
| All (n = 126) | ||||||||||
| Range | 0.001 to 0.125 | 0.001 to 1 | 0.004 to 2 | 0.125 to >16 | 0.125 to >16 | 0.016 to 16 | 0.125 to 8 | 0.008 to >8 | 0.001 to >8 | 0.25 to >8 |
| MIC50/MEC50 | 0.008 | 0.016 | 1 | 2 | 8 | 2 | 1 | 4 | 1 | 1 |
| MIC90/MEC90 | 0.032 | 0.125 | 2 | 4 | >16 | 8 | 2 | >8 | >8 | >8 |
| GM | 0.005 | 0.013 | 0.85 | 1.31 | 4.08 | 1.9 | 1.12 | 1.35 | 0.51 | 1.18 |
| Clinical (n = 47) | ||||||||||
| Range | 0.001 to 0.125 | 0.001 to 1 | 0.004 to 2 | 0.125 to >16 | 1 to >16 | 0.016 to >16 | 0.125 to 2 | 0.008 to >8 | 0.001 to >8 | 0.25 to >8 |
| MIC50/MEC50 | 0.004 | 0.016 | 1 | 2 | >16 | 2 | 1 | 8 | 0.064 | 4 |
| MIC90/MEC90 | 0.032 | 0.064 | 2 | 4 | >16 | 8 | 2 | >8 | >8 | >8 |
| GM | 0.005 | 0.014 | 0.88 | 1.88 | 3.48 | 1.7 | 1.02 | 2.69 | 0.09 | 1.64 |
| Environmental (n = 79) | ||||||||||
| Range | 0.001 to 0.125 | 0.001 to 0.5 | 0.5 to 2 | 0.125 to 8 | 0.125 to >16 | 0.125 to >16 | 0.125 to 8 | 0.008 to >8 | 0.008 to >8 | 0.5 to >8 |
| MIC50/MEC50 | 0.008 | 0.008 | 1 | 1 | 8 | 2 | 1 | 4 | 1 | 8 |
| MIC90/MEC90 | 0.032 | 0.125 | 1 | 4 | >16 | 8 | 2 | >8 | >8 | 8 |
| GM | 0.006 | 0.012 | 0.83 | 1.07 | 4.21 | 2.03 | 1.15 | 2.04 | 1.64 | 5.17 |
a
LULI, luliconazole; LANO, lanoconazole; EFINA, efinaconazole; (VRC), voriconazole; ITC, itraconazole; AMB, amphotericin B; NATA, natamycin.
b
Echinocandins: CFG, caspofungin; MFG, micafungin; AFG, anidulafungin.