TABLE 2.
Compound | MIC (μg/ml) for Candida isolate |
|||||
---|---|---|---|---|---|---|
C. albicans SC5314 | C. parapsilosis ATCC 22019 | C. glabrata ATCC 90030 | C. glabrata Cg003a | C. tropicalis Ct016 | C. krusei ATCC 6258 | |
ZAC989 | 0.6 | 0.8 | 0.9 | 0.6 | 0.9 | 0.8 |
ZAC307 | 0.4 | 0.4 | 0.2 | 0.2 | 0.4 | 0.4 |
ZAC623 | >54 | >54 | NDb | ND | ND | >54 |
This strain has mutations resulting in increased efflux pump activity compared to that of wild-type isolates (34).
ND, not determined.