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. 2018 Apr 27;8:6653. doi: 10.1038/s41598-018-24424-w

Figure 6.

Figure 6

Ingenuity pathway analysis (IPA) of miR-152-3p-target interactions in prostate cancer signalling. Prostate cancer signalling was among the top ten canonical pathways consisting of eight deregulated miR-152-3p target genes (highlighted in purple) i.e. FGFR3, IRS1, SOS2, HSP90AA1, KRAS, CDKN1B, CCND1 and PTEN where FGFR3 and IRS1 are closely related to PI3K and hence shown as a group. Some of the targets for e.g. HSP90, KRAS and SOS exist as a complex or group of genes. The p value was represented as −log p = 5.57 for the analysis.