Skip to main content
. 2018 Mar 23;10(4):134. doi: 10.3390/toxins10040134

Figure 2.

Figure 2

Duration of action of BoNT/A1 and BoNT/B1 in reducing compound 48/80 and chloroquine induced scratching: Mice were treated with intradermal saline (control), BoNT/A1 (1.5 U), or BoNT/B1 (1.5 U) at 2, 7, 14, or 21 days prior to intradermal administration of compound 48/80 (A,B) or Chloroquine (C,D). The total scratches per minute were observed over a 40 min time interval after administration of compound 48/80 or chloroquine. Plots indicate mean ± SEM for cumulative flinches observed at days 2, 7, 14 and 21. ** p < 0.01, *** p < 0.001 vs. saline; # p < 0.05, ## p < 0.01, ### p < 0.001 as compared to saline, N = 8 animals per group.