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. 2018 Apr 2;10(4):146. doi: 10.3390/toxins10040146

Figure 2.

Figure 2

Effects of bvPLA2 on expression of serum total immunoglobulin E (IgE) and cytokines in the ear tissues of DFE/DNCB-induced AD mice via CD206. The total serum IgE levels and the concentration of Th1 and Th2 cytokines were measured by ELISA and Foxp3 expression was observed by western blot. (A) IgE; (B) Interleukin-4 (IL-4); (C) Interleukin-10 (IL-10); (D) Interleukin-6 (IL-6); (E) Interferon- γ (IFN-γ) and (F) Foxp3. The data are shown as the means ± SD. The statistical analyses were conducted with a one-way ANOVA followed by Newman–Keuls multiple comparison tests. CON: normal control, AD: DFE/DNCB treatment, and AD+bvPLA2: DFE/DNCB treatment + bvPLA2 treatment. (** p < 0.01, * p < 0.05 vs. Control and # p < 0.05, NS vs. AD; n = 3–5).