Table 2.
Clinical and laboratory variables at D1 and D7 for the 17 patients, divided in survivors (S, 9 pts) and non-survivors (NS, 8 pts).
| D1 | D7 | |||
|---|---|---|---|---|
| S | NS | S | NS | |
| Heart Rate (bpm) | 103.5 ± 28.4 | 106.1 ± 12.8 | 80.4 ± 11.0 | 91.1 ± 8.7 |
| Mean Arterial Pressure (mmHg) | 76. 6 ± 18.3 | 72.0 ± 11.0 | 96.3 ± 13.8* | 78.4 ± 12.0* |
| Central Venous Pressure (mmHg) | 11.4 ± 5.8 | 11.5 ± 4.4 | 7.9 ± 5.1 | 8.8 ± 2.1 |
| Urine output (mL/day) | 2556.1 ± 918.4 | 1840.0 ± 1652.8 | 3705.6 ± 1580.2* | 1737.5 ± 1478.9* |
| FiO2 (%) | 59.7 ± 12.4 | 56.3 ± 20.8 | 40.6 ± 8.5 | 46.3 ± 23.4 |
| ScvO2 (%) | 73.3 ± 11.6 | 78.5 ± 7.5 | 77.1 ± 7.3 | 77.9 ± 4.5 |
| PvCO2 (mmHg) | 46.8 ± 5.7 | 47.8 ± 4.9 | 50.6 ± 5.2 | 46.5 ± 7.8 |
| PaCO2 (mmHg) | 42.3 ± 6.3 | 44.3 ± 6.4 | 45.3 ± 3.9 | 41.6 ± 8.3 |
| PvO2 (mmHg) | 43.3 ± 4.6 | 46.5 ± 7.4 | 44.1 ± 5.9 | 44.6 ± 5.9 |
| PaO2 (mmHg) | 122.2 ± 61.0 | 98.5 ± 32.0 | 126.9 ± 29.8 | 115.1 ± 61.0 |
| PEEP (cmH2O) | 8.5 ± 2.5 | 5.3 ± 5.4 | 8.9 ± 2.4 | 8.6 ± 3.4 |
| Lactate (mmol/L) | 3.0 ± 1.6 | 5.0 ± 2.3 | 1.4 ± 0.5 | 2.4 ± 2.2 |
| Platelets (×103/mm3) | 63.9 ± 35.4 | 61.4 ± 68.1 | 112.0 ± 67.2 | 80.3 ± 50.9 |
| Creatinine (mg/dL) | 2.7 ± 0.9 | 2.1 ± 1.3 | 1.8 ± 1.7 | 1.8 ± 1.5 |
| Biluribin (mg/dL) | 1.7 ± 0.9 | 5.0 ± 4.8 | 1.9 ± 1.3 | 9.1 ± 10.8 |
| Presepsin (µg/L) | 1486 ± 1256 | 2673 ± 2351 | 830 ± 458 | 4969 ± 5826 |
| Renal Repl Therapy (RRT)[no. (%)] | 0 (0%) | 2 (25%) | 1 (11%) | 3 (38%) |
| Ventilatory Support [no. (%)] | 9 (100%) | 8 (100%) | 4 (44%) | 7 (88%) |
| Sofa score | ||||
| Overall | 11.3 ± 2.4 | 12.4 ± 3.2 | 5.0 ± 2.1 | 9.3 ± 5.1 |
| Respiratory System | 2.4 ± 1.0 | 2.4 ± 1.3 | 1.2 ± 0.8 | 1.9 ± 1.0 |
| Coagulation | 2.3 ± 0.9 | 2.5 ± 1.4 | 1.6 ± 1.1 | 1.9 ± 1.2 |
| Liver | 1.1 ± 0.9 | 1.9 ± 1.2 | 1.0 ± 1.0 | 2 ± 1.8 |
| Cardiovascular System | 3.6 ± 0.5 | 3.6 ± 0.5 | 0.0 ± 0.0 | 1.1 ± 1.5 |
| Renal System | 1.9 ± 0.6 | 2.0 ± 1.7 | 1.2 ± 1.5 | 2.4 ± 1.8 |
Data are presented as mean ± SD or as frequency. Mean Arterial Pressure and Urine output (marked with *) at D7 were significantly different between the two groups (p-value < 0.05 Wilcoxon rank-sum test).