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. 2018 Apr 10;10(4):115. doi: 10.3390/cancers10040115

Figure 2.

Figure 2

YAP/TAZ regulation by integrins and Src. Summarized are pathways that we discussed that influence YAP/TAZ activity downstream of Src or integrins. Pathways that activate YAP or TAZ are depicted as black lines, whereas inhibitory pathways are shown in red. Several of the integrin studies did not directly implicate FAK/Src signaling (indicated by FAK/Src? or Src?) but given what is known about integrin signaling cascades it is probable that they are involved.