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. 2018 Apr 16;10(4):119. doi: 10.3390/cancers10040119

Figure 3.

Figure 3

NF-κB activation upregulates Qp-EBNA1 expression. The nasopharyngeal epithelial (NPE) cell lines NP361hTERT-EBV (A) and NP460hTERT-EBV (B) and the gastric cell line AGS-BX1 (C) were stimulated with poly(I:C) for 16 h. RT-qPCR was performed to analyze changes in the expression of the NFKBIA, BCL2L11, Qp-EBNA1, LMP1, and RPMS1 genes. Gene expression is shown as fold change mRNA expression relative to that of GAPDH. The averages and SEM from at least two independent experiments are shown. Statistical significance was calculated using the two-tailed Student’s t-test. * p < 0.05, ** p < 0.01, *** p < 0.001.