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. 2018 Apr 21;10(4):125. doi: 10.3390/cancers10040125

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Gene delivery by RGD4C-AAVP in vitro into M21 cells 6 days post vector transduction with and without adjuvants. (a) Control (untreated cells) and non-targeted AAVP did not show any GFP expression, while targeted AAVP showed some transgene expression. (b) Sodium butyrate (NaBu) increased transgene expression in M21 cells. (c) C1A increased transgene expression in M21 in a dose dependent manner and more profoundly than the sodium butyrate. The experiment was repeated twice in triplicates and the results shown are representative of one experiment. Images are shown at 20× magnification.