Figure 4.

The effect of 1–4 on cell viability in RAW 264.7 macrophages. Cells were stimulated with LPS (1 μg/mL) in the presence of compounds (6.25, 12.5, 25, 50 μg/mL) for 24 h at 37 °C. The cell viability was assessed by MTT (3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide) assay. Values are expressed as means ± S.D. of triplicate experiments. * p < 0.05 indicates significant differences from the lipopolysaccharide (LPS)-stimulated group.