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. 2018 Mar 27;16(4):105. doi: 10.3390/md16040105

Figure 5.

Figure 5

GTX induces A549/ADR cell death via the mitochondria-dependent pathway. Cells were treated with 0, 0.125, 0.25, and 0.5 µM GTX for 24 h and cell lysates were subjected to western blotting for various apoptosis-related markers including p53, phosphorylated p53 (p-p53), p21, PUMA, Bax, PARP, cleaved PARP (c-PARP), cleaved caspase-9 (c-caspase-9), cleaved caspase-8 and Bid. β-actin was used as a loading control. The graphs are the densitometric quantification of the western blotting result (* p < 0.05).