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. 2018 Mar 27;10(4):152. doi: 10.3390/v10040152

Figure 1.

Figure 1

Identification of R. rosea extract as Ebola virus (EBOV) specific inhibitor. (a) A Traditional Chinese medicines (TCM) extract library of 373 extracts from 128 TCMs was screened against pseudoypted EBOV, H5N1, and H7N1 viruses at a final concentration of 12.5 μg/mL. Only R. rosea extract shows >90% inhibition against EBOV and <30% inhibitioin against H5N1 and H7N1 pseudovirions; (b) The R. rosea extract was further validated by various pseudovirions, including EBOV, MARV, H5N1, and H7N1 at a final concentration of 12.5 μg/mL. Data are means ± SD from three independent experiments. * p < 0.05, EBOV, MARV as compared to H5N1 group; *** p < 0.001, EBOV, MARV when compared to H7N1 group.