Table 1.
EV71 infection-associated toll-like receptors (TLRs). Abbreviations employed: monocyte-derived macrophages (MDMs), peripheral blood mononuclear cells (PBMCs), DCs, plasmacytoid dendritic cells (pDCs).
| TLRs | Ligand | Cell Type | Species | References |
|---|---|---|---|---|
| TLR? | No data | Intestinal epithelial cells | Human | [44] |
| TLR2 | No data | MDMs | Human | [60] |
| TLR3 | No data | DCs, PBMCs | Mouse, Human | [26,60] |
| TLR4 | PAMPs (dsRNA?) | DCs, PBMCs | Mammalian cells, Human | [57,60] |
| TLR7 | DAMPs? | 16HBE, MDMs, PBMCs | Human | [41,58,60] |
| TLR8 | No data | MDMs | Human | [60] |
| TLR9 | Endogenous DNA | pDCs | Mouse | [13] |