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. 2018 Apr 20;10(4):210. doi: 10.3390/v10040210

Figure 4.

Figure 4

CD8+ cells are higher in the blood of CO compared with FIV cats at 0, 1 and 2 weeks FIV-PI (P = 0.0015, P = 0.045, P = 0.011, respectively). CD8+ cells in CO cats are similar to SHAM cats at all time points (P > 0.05), whereas FIV cats had decreased levels compared with SHAM cats at 0, 1 and 2 weeks FIV PI (P = 0.005, 0.0136, and 0.003, respectively) (A). CD8+FAS+ cells in the CO cats were higher than SHAM cats at all of the time points (0 week, P = 0.00098; 1 week, P = 0.0198; 2 weeks, P = 0.0292; 4 weeks, P = 0.00135), and higher in FIV as compared with SHAM cats at 2 and 4 weeks FIV PI (P = 0.02577, 0.00088, respectively) (B). Large granular lymphocyte (LGL) numbers mirrored the CD8+FAS+ cell populations, and differences were trending at one week (P = 0.074) and were significant at two weeks (P = 0.002) FIV PI between CO and FIV cats. Significant differences in LGLs were trending at one week (P = 0.074) and were significant at two weeks FIV PI in between the CO and FIV cats (P = 0.002). LGLs were higher in the CO than SHAM cats at 2, 3, and 4 FIV PI (P = 0.0076, 0.0059, and 0.0044, respectively). However, no significant difference was found in LGL numbers between the FIV and sham inoculations of media (SHAM) cats at any time point (C). Bars indicate statistical differences between the indicated groups. Significant differences were also noted among the three groups over time (CD8+ cells, P = 0.0005; CD8+FAS+ cells, P = 0.0004; LGLs, P = 0.003).