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. 2018 Apr 20;10(4):210. doi: 10.3390/v10040210

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© 2018 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Linear regression analysis to determine cell phenotypes and cytokine expression that was different between the PLV (CO) and SHAM cats at week zero or time of FIV inoculation could predict future outcomes of FIV infection in CO cats. Higher CD8⁺FAS⁺ (A) and CD4⁺CD134⁺ (B) cell numbers in the blood of CO cats (those previously infected with PLV) at week 0 could predict lower FIV proviral loads in blood at one week FIV-PI, and that higher B220⁺CD21⁺ (C) cell numbers in blood at week zero could predict lower FIV plasma viremia at one week FIV PI. Higher IL-10 mRNA expression in PLV-cats at week 0 predicted lower FIV proviral loads at two weeks FIV PI (D).