Table 2.
Cell subsets examined in the different tissue compartments and the proposed function of each phenotype.
| Cell Subsets Examined | Tissue Compartments Examined | Proposed Function |
|---|---|---|
| CD4+ | Blood, Thymus, MLN, PLN | T cells, helper of cytotoxic |
| CD8+ | Blood, Thymus, MLN, PLN | Cytotoxic T cells, NKT cells |
| CD14+ | Blood, Thymus, MLN, PLN | Monocytes, Macrophages, myeloid DC |
| CD4+ CD134+ | Blood, Thymus, MLN, PLN | Activated CD4+ T cells |
| CD8+ FAS+ | Blood | Activated CD8+ T cells |
| CD4+ MHC II+ | Blood, Thymus, MLN, PLN | Activated CD4+ T cells |
| CD4+ CD45RA+ | Blood, Thymus | Naïve CD4+ T cells |
| CD8+ CD45RA+ | Blood, Thymus | Naïve CD8+ T cells |
| CD4+ CD8+ | Thymus | Double-positive T cells |
| CD4− CD8− | Thymus | Double-negative T cells |
| CD4+ CD25+ | Blood | Activated or Regulatory CD4+ T cells |
| B220+ CD21+ | Blood | B cells |
MLN = mesenteric lymph node, PLN = peripheral lymph node.