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Doxorubicin (DOX) uptake by cancer and normal cells. DOX uptake by cancer (a) HeLa and (b) HT29 cells, and normal (c) 3T3 and (d) CCD-112 cells incubated with DOX alone, DOX-conjugated tHBcAg VLNPs (tHBcAg-DOX), dual-conjugated tHBcAg VLNPs with folic acid (FA) and DOX (FA-tHBcAg-DOX). Data represent means ± standard deviations (SD) of triplicate determinations.
