Table 3.
Adverse events during induction BR (worst grade toxicity per patient, n=34).
| Gr 3 (%) | Gr 4 (%) | Gr 5 (%) | |
|---|---|---|---|
| Hematologic toxicities: | |||
| Leukopenia | 5 (15%) | 5 (15%) | — |
| Neutropenia | 6 (18%) | 14 (41%) | — |
| Anemia/hemoglobin | 1 (3%) | — | — |
| Thrombocytopenia | 5 (15%) | 2 (6%) | — |
| Infections: | |||
| Febrile neutropenia | 4 (12%) | — | — |
| Infections | 10 (30%) | 1 (3%) | 1 (3%) |
| Non-hematologic toxicities: | |||
| Failure to thrive | 1 (3%) | — | — |
| Fatigue | 2 (6%) | — | — |
| Nausea | 1 (3%) | — | — |
| Emesis | 2 (6%) | — | — |
| Anorexia | 1 (3%) | — | — |
| Diarrhea | 3 (9%) | — | — |
| Dysphagia | 1 (3%) | — | — |
| Heart failure | — | — | 1 (3%) |
| Hyperglycemia | 1 (3%) | — | — |
| Hypokalemia | 1 (3%) | — | — |
| Hypophosphatemia | 2 (6%) | — | — |
| Elevated AST/ALT | 4 (12%) | — | — |
| Hyponatremia | 1 (3%) | — | — |
| Tumor lysis syndrome | 1 (3%) | — | — |