Table 5.
Cox proportional hazards model to predict Death
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| HR | 95% CI | P | HR | 95% CI | P | |
|
| ||||||
| Age per decade | 1.78 | 1.06 – 2.97 | 0.03 | |||
|
| ||||||
| Male Gender | 1.24 | 0.51 – 3.05 | 0.64 | |||
|
| ||||||
| BMI (Kg/m2) | 1.07 | 1.01 – 1.13 | 0.03 | |||
|
| ||||||
| Diagnosis | ||||||
| Hepatitis C | 5.08 | 1.72 – 15.02 | <0.01 | |||
| Hepatitis B | 0.66 | 0.09 – 4.94 | 0.69 | |||
| Alcohol | 0.31 | 0.04 – 2.33 | 0.26 | |||
| Other | 0.19 | 0.04 – 0.82 | 0.03 | |||
|
| ||||||
| Time dependent post-LT CKD | 36.83 | 4.86 – 267.15 | <0.01 | 30.25 | 4.73–193.48 | <0.01 |
|
| ||||||
| DM | ||||||
| Before LT | 2.000 | 0.85 – 4.69 | 0.11 | |||
| After LT | 2.995 | 1.22 – 7.35 | 0.02 | 2.97 | 1.20–7.31 | 0.02 |
|
| ||||||
| Hypertension | ||||||
| Before LT | 2.407 | 1.03 – 5.63 | 0.04 | |||
| After LT | 1.863 | 0.69 – 5.05 | 0.22 | |||
|
| ||||||
| LDLT | 0.600 | 0.14 – 2.57 | 0.49 | |||
|
| ||||||
| HCC | 2.45 | 1.05 – 5.74 | 0.04 | |||
|
| ||||||
| Calculated MELD | 1.000 | 0.96 – 1.05 | 1.00 | |||
|
| ||||||
| Cyclosporine as initial CNI (%) | 5.536 | 2.04 – 15.02 | <0.01 | |||
|
| ||||||
| Cold Ischemic Time (per hour) | 1.09 | 0.99 – 1.10 | 0.13 | |||
|
| ||||||
| Pre-LT MDRD eGFR (per 10 mL/min/1.73m2) | 0.97 | 0.87 – 1.08 | 0.59 | |||
|
| ||||||
| uNGAL at 24h PR (per 100 ng/ml) | 1.01 | 0.88—1.17 | 0.85 | |||