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. 2018 Apr 27;23:17. doi: 10.1186/s11658-018-0070-8

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Knockdown of SNHG8 inhibits cell proliferation and clonogenic potential in GT38 cells. a The specific shRNA sh-SNHG8 decreased the SNHG8 level by up to 57% in GT38 cells. **p < 0.01. b The results of 3 consecutive days of cell viability assessments for GT38 cells with (KD group) or without (NC group) specific shRNA transfections and blank control cells (CON group). c GT38 cells with (KD group) or without (NC group) specific shRNA transfections and blank control cells (CON group) were subjected to colony formation assays. After crystal violet staining, colonies were visually observed. d Counting of colonies showed that colony numbers had significantly decreased in the KD group. **p < 0.01 compared with NC group. CON, blank control cells without transfection; NC, negative control; KD, SNHG8 knockdown