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. 2018 Apr 27;18:486. doi: 10.1186/s12885-018-4406-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The fundus photographs of group A-E eyes of retinoblastoma. Group A: Eyes with small discrete tumors away from critical structures; Group B: Eyes with no vitreous or subretinal seeding and discrete retinal tumor of any size or location; Group C: Eyes with only focal vitreous or subretinal seeding and discrete retinal tumors of any size and location; Group D: Eyes with diffuse vitreous or subretinal seeding and/or massive, nondiscrete endophytic or exophytic disease; Group E: Eyes that have been destroyed anatomically or functionally by the tumor