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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: J Biomed Mater Res A. 2018 Mar 5;106(6):1463–1475. doi: 10.1002/jbm.a.36348

Figure 3. Colocalization of NO and SNO-NP fluorescence in lymph nodes (LN) draining site of injection demonstrates nanoparticle-mediated lymphatic transport facilitates NO delivery to LN.

Figure 3

Representative IVIS images (A, C) and quantification (B, D) of AlexaFluor647 (A–B) and NO probe DAF-FM DA (C–D) fluorescence in draining LN associated with SNO-NP, but not SNAP administration in the forelimb skin. White arrow, intradermal site of treatment group injection; white circle, LN draining the site of intradermal injection; yellow circle, DAF-FM DA injected LN.