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. 2018 Apr 27;15:125. doi: 10.1186/s12974-018-1162-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Specific elevation of CSF mtDNA in patients with NMOSD. mtDNA levels in CSF were significantly higher in patients with NMOSD in acute phase than in patients with MS in acute phase and other neurological diseases (GBS, ALS, iNPH, cervical spondylosis, and somatic symptom disorders) (a–c). The total amount of DNA was not significantly different among these groups (d). The data are expressed as means ± SEM. *p < 0.05; **p < 0.01; NS not significant (P ≥ 0.05)