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. 2018 Apr 27;15:125. doi: 10.1186/s12974-018-1162-0

Fig. 6.

Fig. 6

IL-1β production by DNA fraction containing abundant mtDNA is dependent on NLRP3 inflammasome and TLR9. IL-1β secretion was suppressed by inhibitors of the NLRP3 inflammasome (MCC950) and TLR9 (ODN2088) in PBMCs. The results are the representative of two independent experiments. The data are expressed as means ± SEM. *p < 0.05