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Regulation by miR-29. miR-29 inhibits the translation of BACE1, several Bcl-2 Homology 3 (BH3)-only family proteins (Bim, Bmf, Hrk, Puma, and N-bak), SPTLC2 and neuron navigator 3 (NAV3). The debatable levels of miR-29 expression in AD brain are indicated by the yellow tilde symbol (~), as are the hypothetical expression levels of the proteins regulated by miR-29 and their cellular effects.
