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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2017 Dec 12;235(5):1347–1359. doi: 10.1007/s00213-017-4798-z

Figure 3. mRNA expression for glutamatergic genes in the dmPFC.

Figure 3

A) Prolonged-access to cocaine resulted in increased levels of Homer2 mRNA within the dmPFC after 1 day of withdrawal. B) Prolonged-access to cocaine resulted in increased levels of Grin1 mRNA within the dmPFC after 1 day of withdrawal. C) Prolonged-access to cocaine resulted in increased levels of Dlg4 mRNA within the dmPFC after 1 day of withdrawal. D) Homer2 mRNA was positively correlated with total cocaine infusions in the prolonged access group (R2 = 0.1975, p < 0.05). E) Homer2 mRNA was positively correlated with total cocaine infusions in the limited access group (R2 = 0.4763, p < 0.05). F) Homer2 mRNA was negatively correlated with total cocaine infusions in the limited + yoked access group (R2 = 0.4046, p < 0.05).