Table 1.
Patient characteristics at study entry by treatment arm (N=321)
| Variable | Sunitinib | Sorafenib | Placebo | P value | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| N | % | N | % | N | % | ||
| Age at registration (mean, SD) | 53.8 | 10.7 | 54.8 | 10.1 | 56.6 | 9.6 | 0.123 |
| Sex | 0.261 | ||||||
| Male | 78 | 72.9 | 59 | 62.1 | 80 | 67.2 | |
| Female | 29 | 27.1 | 36 | 37.9 | 39 | 32.8 | |
| Ethnicity | 0.444 | ||||||
| White | 101 | 97.1 | 81 | 94.2 | 109 | 97.3 | |
| Other | 3 | 2.9 | 5 | 5.8 | 3 | 2.7 | |
| ECOG PS | 0.694 | ||||||
| 0 | 83 | 79.1 | 73 | 81.1 | 90 | 76.3 | |
| 1 | 22 | 21.0 | 17 | 18.9 | 28 | 23.7 | |
| Fatigue present prior to surgery | 0.572 | ||||||
| No | 73 | 79.4 | 67 | 81.7 | 91 | 85.1 | |
| Yes | 19 | 20.7 | 15 | 18.3 | 16 | 15.0 | |
| Fatigue present after surgery | 0.806 | ||||||
| No | 72 | 73.5 | 66 | 73.3 | 83 | 76.9 | |
| Yes | 26 | 26.5 | 24 | 26.7 | 25 | 23.2 | |
| How was disease discovered | 0.846 | ||||||
| Incidental | 37 | 34.6 | 29 | 30.9 | 40 | 33.6 | |
| Symptomatic | 70 | 65.4 | 65 | 69.2 | 79 | 66.4 | |
| History of cardiovascular disease | 0.436 | ||||||
| No | 86 | 81.1 | 73 | 77.7 | 88 | 74.0 | |
| Yes | 20 | 18.9 | 21 | 22.3 | 31 | 26.1 | |