Figure 3. Mouse lincRNA-p21 is associated a subset of mRNA.
(a) Schematic of target mRNAs containing partial complementarity with mouse lincRNA-p21. (b) Schematic of affinity pull down using MS2 aptamer for mouse lincRNA-p21 enrichment. (c) List of representative mRNAs enriched in mouse lincRNA-p21 pull down and cDNA microarray from mouse embryonic fibroblasts. (d) Existence of RNA-RNA interaction was validated by MS2 pulldown and UV crosslinking followed by qPCR analysis. *p<0.05 (student’s t-test), compared with control condition.