Table 3.
Differences in the major tolerance strategies in clinical kidney transplantation
| Program | Conditioning Regimen | Timing of Conditioning Regimen | Hematopoietic Cell Transplant | Chimerism Goal |
|---|---|---|---|---|
| Massachusetts General Hospital 1998- | Chemotherapy + thymic irradiation | Pre-kidney transplant | Unselected | Transient mixed |
| Stanford 2000- | rATG + total lymphoid irradiation | Post-kidney transplant | Selected | Mixed |
| Northwestern 2009- | Chemotherapy + total body irradiation | Pre-kidney transplant | Selected + “facilitator” cell | Complete |