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. Author manuscript; available in PMC: 2018 Apr 29.
Published in final edited form as: Sex Health. 2016 Apr;13(2):155–161. doi: 10.1071/SH15124

Table 4.

HIV treatment-related outcomes for males and females: time to virological suppression; time to virological failure after first instance of viral suppression; and time to switch of first-line ART anchor agent

End-point Hazard ratio
(Female
vs Male)		 95%
confidence
intervals		 P-value
Time to pVL suppression
  Univariate 1.18 0.99–1.39 0.06
  MultivariableA 1.08 0.91–1.28 0.37
Time from pVL suppression to pVL failure
  Univariate 1.10 0.81–1.26 0.95
  MultivariableA 0.97 0.77–1.21 0.76
Time to switch of first-line ART anchor agent
  Univariate 1.03 0.81–1.30 0.82
  MultivariableA 1.05 0.83–1.34 0.67

pVL, plasma viral load; ART, antiretroviral therapy

A

Adjusted for age at ART initiation, injecting drug use HIV exposure, hepatitis C virus, hepatitis B virus, CD4 cell count at ART initiation, HIV viral load ≥100 000 copies mL−1 at ART initiation, year of ART initiation and clinical care setting.