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. 2018 Apr 30;9(5):483. doi: 10.1038/s41419-018-0518-9

Fig. 1. Impaired autophagy during I/R contributes to intestinal injury.

Fig. 1

a Mice were subjected to 45 min of intestinal ischemia, followed by 0–8 h of reperfusion. Representative immunoblots of endogenous LC3 and BECN1 levels in the intestine. b LC3 and SQSTM1 levels after 45 min of intestinal ischemia followed by 4 h of reperfusion in the absence and presence of CQ. c Representative transmission electron microscopy images and quantitative analysis of AVs in the intestine, n = 3. Arrows indicate the AVs. d Representative H&E staining and histological injury scores of the gut in the different groups, n = 6. *P < 0.05, **P < 0.01 versus sham. ##P < 0.01 versus sham+CQ