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. 2018 Apr 23;8:121. doi: 10.3389/fcimb.2018.00121

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Copyright © 2018 Clemens, Lee and Horwitz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic organization of the T6SS gene cluster on the FPI. Names of F. novicida gene products are shown above and names of the corresponding canonical T6SS gene products (where known) are shown below. Gene products shown in blue are required for growth in macrophages and for virulence in animals; those in orange are required for full virulence in animals (Weiss et al., 2007a) but not for growth in macrophages; and those in green are not required for growth in macrophages or for virulence in animals (Bröms et al., 2010).