Fig. 6.

Functional analysis of CARIC RBPs. (A) KEGG pathways enriched in the CARIC unknown RBPs. (B) Various proteasome components were identified as RBPs. In the schematic of the human proteasome, proteins color-coded in orange are CARIC class I RBPs, proteins in blue are CARIC class II RBPs, and proteins in gray are potenital CARIC RBPs (i.e., proteins identified with a fold change between one and two). (C) Number of CARIC-annotated RBPs and unknown RBPs that are metabolic enzymes. (D) Number of CARIC unknown RBPs in specific metabolic pathways. (E) Number of CARIC-annotated RBPs and unknown RBPs listed in OMIM.