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. 2018 Apr 10;115(17):E4013–E4022. doi: 10.1073/pnas.1800505115

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Fig. 1. — Genome-wide RNAi screening identifies a role for CSE1L in EGFP reporter silencing. (A) Experimental scheme of the high-content RNAi screening. (Magnification: 10×.) (B) Plot of the coefficients of variation (CV%) among three biological replicates and the mean R_GFP for each of the confirmed hits, verified with at least two independent siRNA pairs. The scale of the y axis below 20 was adjusted for clarity. (C) Validation with eight independent siRNA pairs for CSE1L. Cell images (Left), knockdown efficiency (Upper Right), and R_GFP values (Lower Right) of each siRNA pair are shown. Error bars represent SD.