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DNA densities at the core surface (blue) or outer surface (red) as a function of core size for hypothetical SNAs with 6 to 16 strands per particle. The DNA is assumed to be 6 nm in length (18-mer in B-DNA form). To accommodate 10 strands on the particle while maintaining an outer surface density of >1.5 pmol/cm2, the combined core and linker size should be in a narrow window of ∼4.0 nm to 6.7 nm (indicated by a gray box).
