Figure 4.

1,25(OH)₂D₃ regulated lipid metabolism in MSG rats. (A)–(C) 1,25(OH)₂D₃ treatment decreased the level of serum TG, but did not change the levels of serum CHO and LDL-C. (D) The mRNA expression of Pparα in liver was tested by RT-PCR. (E) Liver sections were stained with H&E as described in methods. 1,25(OH)₂D₃ treatment inhibited MSG-induced fatty infiltration in liver. (F) Representative H&E staining of fat tissue sections. (G) 1,25(OH)₂D₃ treatment reduced adipocyte diameters (max and min) as measured with H&E staining. Data are expressed as mean±SEM, n=10. ^#P<0.05, ^##P<0.01 vs. normal group; ^*P<0.05, ^**P<0.01 vs. MSG group.