Table 2.
Summary demographics of infants at inclusion in the population pharmacokinetic analysis
| Day | Group number | N | Mean age (days) (CV%) | Median age (days) (range) | Mean weight (kg) (CV%) | Median weight (kg) (range) |
|---|---|---|---|---|---|---|
| D1 | Both Groups | 22 | 103 (34.1%) | 104 (50‐151) | 5.6 (21%) | 5.5 (3.6‐8.5) |
| #1 | 10 | 70 (19.6%) | 72 (50‐89) | 4.8 (15%) | 4.8 (3.6‐5.9) | |
| #2 | 12 | 131 (14.0%) | 135 (95‐151) | 6.4 (16%) | 6.2 (5.2‐8.5) | |
| D7 | Both Groups | 10 | 110 (32.3%) | 112 (56‐159) | 5.82 (19.4%) | 5.71 (4.0‐8.5) |
| #1 | 10 | 76 (18.4%) | 79 (56‐96) | 5.05 (15.0%) | 5.04 (4.0‐6.2) | |
| #2 | 10 | 139 (13.0%) | 141 (103‐159) | 6.46 (15.3%) | 6.15 (5.4‐8.5) | |
| D14 | Both Groups | 12 | 118 (30.0%) | 119 (63‐166) | 5.98 (17.7%) | 5.9 (4.2‐8.05) |
| #1 | 12 | 84 (16.6%) | 86 (63‐103) | 5.25 (13.7%) | 5.25 (4.2‐6.27) | |
| #2 | 12 | 146 (12.3%) | 149 (110‐166) | 6.59 (13.8%) | 6.45 (5.4‐8.05) | |
| D28 | #1 | 10 | 98 (14.4%) | 101 (77‐118) | 5.62 (12.8%) | 5.6 (4.5‐6.77) |
| D84 | #2 | 12 | 216 (8.49%) | 216 (180‐243) | 7.78 (13.3%) | 7.65 (6.4‐9.7) |