Table 7.
Individual values and descriptive statistics of apparent clearance of propranolol predicted using the final model
| Group | Visit | Patient ID | CL/F (L/h) |
|---|---|---|---|
| 1 | Day 28 | 50105 | 20.7 |
| 50106 | 21.5 | ||
| 50109 | 10.9 | ||
| 50110 | 13.1 | ||
| 50201 | 14.8 | ||
| 50204 | 13.2 | ||
| 50302 | 20.2 | ||
| 50303 | 19.5 | ||
| 50305 | 13.2 | ||
| 50306 | 20.7 | ||
| N | 10 | ||
| Geometric mean (CV%) | 16.3 (25.8%) | ||
| Median (range) | 17.2 (10.9‐21.5) | ||
| 2 | Day 84 | 50101 | 64.1 |
| 50103 | 21.7 | ||
| 50104 | 29.8 | ||
| 50107 | 31.2 | ||
| 50108 | 14.7 | ||
| 50202 | 7.19 | ||
| 50203 | 21.0 | ||
| 50205 | 44.6 | ||
| 50301 | 23.0 | ||
| 50304 | 20.0 | ||
| 50401 | 17.5 | ||
| 50402 | 40.3 | ||
| N | 12 | ||
| Geometric Mean (CV%) | 24.3 (62.1%) | ||
| Median (range) | 22.3 (7.19‐64.1) | ||
ID, Identification, CL/F, apparent total plasma clearance.