Fig. 4.

Human αSyn expression in the SN is associated with abnormal locomotor activity and rotation behavior in mice. Total distance traveled (a), moving duration time (b), velocity (c) and representative movement tracks (d) by open field test 14 weeks post virus injection. n = 5 per group, average of data from two sessions. Amphetamine induced rotations 11 weeks post-injection (e). Venus, n = 6; V1SSV2, n = 7. Data are expressed as the means ± SEM ∗p < 0.05 student t-test (a–c), ANOVA followed by Turkey's post hoc test (e).