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. 2018 Mar 7;8(2):131–136. doi: 10.1016/j.apsb.2018.01.012

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© 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Classical ARV drugs in phase III clinical trials. (A) Tenofovir alafenamide (GS-7340, Vemlidy, C₂₁H₂₉N₆O₅P), a nucleotide reverse transcriptase inhibitor and a prodrug of tenofovir. (B) Doravirine (MK-1439, C₁₇H₁₁ClF₃N₅O₃), a non-nucleoside reverse transcriptase inhibitor. (C) Bictegravir (BIC, GS-9883, C₂₁H₁₈F₃N₃O₅), an integrase inhibitor.