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Entry inhibitors that have reached late stage clinical trials.
| Inhibitor | Development status | Drug class | Action against entry stage |
|---|---|---|---|
| BMS-663068 | Phase III | Small molecular | Binds to region with CD4 |
| Ibalizumab | Phase III | Post-attachment inhibitor (mAb) | Binds to CD4 |
| Aplaviroc | Phase IIb and III | Small molecular CCR5 antagonist | Binds to CCR5 |
| Cenicriviroc | Phase IIb and III | Small molecular CCR5 and CCR2 antagonist | Binds to CCR5 and CCR2 |
| Sifuvirtide | Early phase | Peptides fusion inhibitor | Binds to gp41 |
