. 2017 Dec 25;29(6):328–342. doi: 10.11919/j.issn.1002-0829.217106

Table 2.

GRADE quality of evidence assessment of individual outcome indicators for the efficacy of rTMS combined with antidepressant medication therapy in the treatment of depression

Outcome indicator	No. of sample cases in the included studies	heterogeneity		Model of analysis	Group effect value		Estimated value	95% Confidence interval	GRADE quality of evidence
Outcome indicator	No. of sample cases in the included studies	I²	p	Model of analysis	Z	p	Estimated value	95% Confidence interval	GRADE quality of evidence
Treatment effect	1659	90%	<0.01	Random effect model	4.65	<0.01	0.84(SMD)	-1.19,-0.48	Moderate
Side effect	1353	38%	0.06	Fixed effect model	4.62	<0.01	1.96(RR)	1.47,2.61	Moderate
Drop-out rate	882	0%	0.82	Fixed effect model	0.89	0.37	1.27(RR)	0.75,2.12	Moderate

SMD: standardized mean difference; RR: relative risk;

GRADE: The Grading of Recommendations Assessment, Development and Evaluation