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. 2018 Feb 23;29:159–165. doi: 10.1016/j.ebiom.2018.02.020

Fig. 3.

Fig. 3

Effect of C. trachomatis infection on immortalised human Fallopian tube epithelial OE-E6/E7 cells and an in vitro model of human embryo attachment. (a) Box and whisker plots of relative levels of ITGB1 mRNA expression (measured by qRT-PCR) in Fallopian tube epithelial OE-E6/E7 cells following exposure to C. trachomatis for 24 h (MOI = multiplicity of infection). The boxes represent mean values ±1 standard deviation and the whiskers denote the full range of the data. Data are the mean of six biological replicates. (*P < 0.05, Kruskal-Wallis test with Dunn's multiple comparisons post-test). (b) Trophoblast spheroid-oviductal epithelial cell attachment following 24 h exposure to C. trachomatis ±1 h pre-treatment with 0.1 μg/ml anti-ITGB1 antibody. The box-and-whisker plots illustrate percentage adherence (number of spheroids attached/total number of spheroids) of SW-71 trophoblast spheroids to oviductal epithelial OE-E6/E7 cells. The boxes represent mean values ±1 standard deviation and the whiskers denote the full range of the data. Data are the mean of four biological replicates. (**** P < 0.0001, one-way Anova and Dunnett's multiple comparisons post-test).