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. 2018 Apr 26;78(4):382–399. doi: 10.1055/a-0582-0122
Consensus-based Recommendation 9.E31
Expert consensus Level of consensus ++
In any case, potentially increased fibrinolytic activity should be treated by the administration of tranexamic acid (an antifibrinolytic) before the substitution of fibrinogen (factor concentrate or FFP) is considered 39 .