Effect of the inoculum on time to positivity. Boxes indicate the quartiles and whiskers the range, and the median is marked as a black line. (A) Differences in time to positivity between OXA-48-like-, KPC-, and NDM-producing isolates for the 1-μl inoculum. (B to D) Impact of inoculum and antibiotics on time to positivity. The 1 μl and 10 μl designate inocula taken distant from the antibiotic disks. Gray boxes indicate 1-μl inoculum that was harvested next to an antibiotic disk. EPM, ertapenem; IPM, imipenem; MER, meropenem. **, P < 0.01; ***, P < 0.001.