TABLE 1.
Isolates included in the study
| Carbapenemase production | No. of isolates |
MIC range (mg/liter) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| K. pneumoniae | E. coli | E. cloacae | E. aerogenes | P. mirabilis | R. ornithinolytica | All species | Ertapenem | Imipenem | Meropenem | |
| Carbapenemase positive | 34 | 10 | 5 | 1 | 1 | 51 | 0.12 to >32 | 0.5 to >32 | 0.12 to >32 | |
| OXA-48-like | 16 | 6 | 1 | 23 | 1 to >32 | 0.5 to >32 | 0.12 to >32 | |||
| OXA-48 | 12 | 1 | 1 | 14 | 1 to >32 | 0.5 to 8 | 0.12 to 16 | |||
| OXA-162 | 2 | 2 | 2 to >32 | 1 to 8 | 0.5 to >32 | |||||
| OXA-181 | 2 | 2 | 2 | 0.5 | 0.25 to 0.5 | |||||
| OXA-204 | 1 | 1 | >32 | 8 | >32 | |||||
| OXA-232 | 2 | 2 | 2 to 4 | 0.5 | 0.25 | |||||
| OXA-244 | 1 | 1 | 2 | 2 to 32 | 0.5 to 32 | 0.25 to 32 | ||||
| KPC | 10 | 10 | 16 to >32 | 32 to >32 | 32 to >32 | |||||
| KPC-2 | 9 | 9 | 16 to >32 | 32 to >32 | 32 to >32 | |||||
| KPC-3 | 1 | 1 | >32 | >32 | >32 | |||||
| NDM | 7 | 3 | 4 | 1 | 1 | 16 | 0.12 to >32 | 4 to >32 | 1 to >32 | |
| NDM-1 | 7 | 1 | 4 | 1 | 1 | 14 | 0.12 to >32 | 4 to >32 | 1 to >32 | |
| NDM-5 | 1 | 1 | >32 | >32 | >32 | |||||
| NDM-7 | 1 | 1 | >32 | >32 | >32 | |||||
| NDM-1/OXA-232 | 1 | 1 | >32 | >32 | >32 | |||||
| NDM-5/OXA-181 | 1 | 1 | 8 | >32 | >32 | |||||
| Carbapenemase negative | 4 | 3 | 3 | 2 | 12 | 8 to 32 | 0.5 to 16 | 1 to 4 | ||
| Total | 38 | 13 | 8 | 2 | 1 | 1 | 63 | |||